Lilly direct-selling Zepbound at $499/mo — compare with 11 other programs

Cialis tadalafil

pronounced as (ta da' la fil)

FDA-approved forErectile dysfunctionBenign prostatic hyperplasia
ED TreatmentBy Eli Lilly· FDA-approved 2003

Long-acting PDE5 inhibitor. 24-36 hour duration. Daily low-dose option for spontaneity.

Cialis product image
Reviewed by the glpzoom Editorial Team against primary clinical sources — FDA labeling, peer-reviewed trials, and specialty-society guidelines.
Content current as of June 2026; updated when guidance or availability changes.

Cialis vs Viagra

Onset vs duration is the real decision. Sildenafil (Viagra) works in 30-60 min for 4-6 hours; tadalafil (Cialis) lasts up to 36 hours for less clock-watching.

CialisViagra
Generic nametadalafilsildenafil
ManufacturerEli LillyPfizer
FDA statusFDA-approved 2003FDA-approved 1998
Clinical efficacy
Pivotal trial
Boxed warningNoNo
Full pageCialisViagra

Deep comparison: Cialis vs Viagra

What is Cialis?

Cialis is the brand-name tadalafil, longer-acting than sildenafil. Generic since 2018. Two dosing modes: as-needed (10-20mg) or daily low-dose (2.5-5mg). The daily mode is popular because it allows spontaneous activity without timing pills.

How does Cialis work?

Same mechanism as sildenafil — PDE5 inhibition. Longer half-life (17.5 hours vs 4 hours for sildenafil) means effect lasts longer per dose.

Who can take Cialis?

Adult men with ED. Daily low-dose also FDA-approved for benign prostatic hyperplasia (BPH). Same contraindications as sildenafil (nitrates, alpha-blockers, etc.).

How is Cialis taken?

As-needed: 10-20mg before sexual activity. Daily: 2.5-5mg every day at the same time.

Cialis — time profile
01.5 days
Onset
30 min
Peak
2h
Effective until
1.5 days

How much does Cialis cost?

Generic tadalafil $1-8/tablet. Telehealth $30-100/month depending on dose and as-needed vs daily.

What side effects can Cialis cause?

Back pain, muscle aches (more common than with sildenafil). Headache, flushing, nasal congestion. Same vision/hearing warnings.

What if I miss a dose of Cialis?

Daily Cialis: if missed, take when remembered if within 12 hours; if longer, skip and resume regular schedule. Do not double up. As-needed Cialis: no missed-dose concept; take 30 minutes before activity, max one dose per 24 hours.

Where to get Cialis

Licensed US telehealth providers that prescribe/ship Cialis. We earn commission when you book. See disclosure.

  • Hims logo

    Hims

    from $13/mo
    • Best for cash-pay
    • Best for speed

    Hims ED — generic sildenafil from $13/mo

    Why we picked it

    Generic sildenafil at roughly half the chewable-competitor per-dose cost, with branded Viagra/Cialis available if you want it.

    Who should skip

    Skip if you want fast-onset chewables — Hims uses standard tablets.

    Off-Rx: no plan
    Flaws but not dealbreakers (2)
    • No chewable format
    • Subscription auto-renews — set a calendar reminder if unsure

    We may earn a commission. Pricing on partner site is final.

  • Ro logo

    Ro

    from $2/mo
    • Best for clinical oversight

    Ro — original online ED brand, sildenafil & tadalafil

    Why we picked it

    Cleaner clinical voice and quarterly auto-ship with reminders means less reorder friction once you've settled on a dose.

    Who should skip

    Skip if you want the lowest entry price — Hims undercuts Ro's starting tier.

    Off-Rx: no plan
    Flaws but not dealbreakers (2)
    • Entry price slightly above Hims
    • No chewable option

    We may earn a commission. Pricing on partner site is final.

Not sure which Cialis program fits?

5 questions, ~60 seconds. We'll match you with three programs and explain the trade-offs.

Start free assessment

No email required. Resume any time.

Preview
Q1

How often do you experience symptoms?

  • Occasional
  • Frequent
  • Almost always
Q2

Have you tried ED medication before?

  • Never
  • Sildenafil (Viagra)
  • Tadalafil (Cialis)

+ 3 more in the full assessment

Ask the urologist

Browse all answers

Related terms

Related topics

How to get it

  1. Take the eligibility quiz

    5 minutes of medical-history questions matched to the medication's FDA criteria. Free, no commitment.

  2. Submit ID + a recent photo

    Required by every legitimate US telehealth platform to verify identity and meet state prescribing rules.

  3. Async clinical review

    A licensed clinician in your state reviews your history and decides whether the medication is appropriate. Typically within 24-48 hours.

  4. Prescription ships

    If approved, the medication is sent from a partner pharmacy. Initial titration dose arrives in 3-7 days for most US states.

  5. Ongoing support

    Most programs include follow-up check-ins, dose adjustments, and side-effect support. Coverage varies by program.

Sources

Primary references this page draws from. We cite original sources so you can verify any claim.

For clinicians: see the Cialis prescribing summary.

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